Multiple symmetric lipomatosis: an unusual cause of childhood obesity and mental retardation

C Kratz, HG Lenard, T Ruzicka, J Gärtner - European Journal of Paediatric …, 2000 - Elsevier
Multiple symmetric lipomatosis (MSL), also known as Launois–Bensaude syndrome or
Madelung's disease, is a rare disorder predominantly seen in middle-aged male patients.
The disorder is characterized by large subcutaneous fat masses distributed around the neck,
shoulders, and other parts of the trunk, often associated with nervous system abnormalities.
A close relationship to alcoholism, metabolic disturbances and malignant tumours has been
observed. Until now, MSL has only been described in adults. We report on the first two …